Wednesday, May 4, 2016

The Proposed Aggregate Exposure Pathway Concept

The cover for Environmental Science and Technology this week is about the Aggregate Exposure Pathway (AEP) concept, a proposal by  Justin Teeguarden at the Pacific Northwest National Laboratory (USA) and colleagues to organize exposure data from the pollutant source to the target site of action.  The proposal is framed around chemical exposures, and feeds in to the already established Adverse Outcome Pathway (AOP) concept from toxicology.  The goal of the AEP is to create a framework that contributes to the evolution of exposure data from an observational science to a predictive science.

How is this relevant to pipes and potties?  In the nutrition and water, sanitation, and hygiene sectors, we're seeing increasing interest in monitoring exposures to both chemicals and microorganisms.  The latter often includes assessments of exposures to both fecal contamination in general and to specific pathogens.  These exposure and risk assessments benefit substantially from advances in the chemical exposure models.

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